Requirements for the moisture content of the desiccant in the effervescent tube

Effervescent tube is a kind of medicine packaging container with excellent moisture-proof performance. On the one hand, its moisture-proof function is realized through strict sealing. On the other hand, silica gel and molecular sieve desiccant are placed inside the package to absorb the internal moisture.

144mm*29mm effervescent tube packaging

For the moisture content of the two desiccants, effervescent tubes also have relevant regulations. In YBB00172004-2015 “Quality Standard for Oral Solid Pharmaceutical Low Density Polyethylene Moisture-Proof Combination Caps”, the requirements for the moisture content of the desiccant are as follows:

caps for effervescent tube

In an environment where the relative humidity of silica gel does not exceed 75%, quickly take out the bottle cap from the closed packaging bag, and take out 5-7g of desiccant from the bottle cap, put it in a weighing bottle (W1) with constant weight, and weigh it. Weight (W2), placed in an oven at 180°C ± 10°C (the total time from opening the bottle cap to the time when the desiccant is placed in the oven should not exceed 5 minutes) to constant weight (weighing as W3), calculated by the following formula, containing water The rate must not exceed 4.8%.

Macromolecular sieve In an environment where the relative humidity does not exceed 75%, quickly take out an appropriate amount of the bottle cap from the closed package, take out the desiccant in the bottle cap with tweezers, and place it in a constant weight crucible W0 (add 8-10g to each crucible). ), accurately weighed W1, placed in a high-temperature furnace at 950°C (the total time from opening the cap packaging bag to placing the desiccant in the high-temperature furnace should not exceed 5 minutes), drying for one hour, taking out the crucible, and accurately weighing after cooling. Determine W2, and calculate according to the following formula, and the moisture content should not exceed 4.8%.

The above are the requirements of the effervescent tube for the moisture content of the desiccant. A qualified desiccant is the basis for ensuring its internal moisture-proof performance and is also an important factor to ensure the stability of the effervescent tablet.

Effervescent Tablet Tube Test Specification

The concept of the inspection result exceeding standard management was introduced for the first time, which means that the test result is beyond the legal standard and the enterprise internal control standard. Excessive inspection results do not necessarily mean that the sample inspection is not qualified. How can the effervescent tablet tube manufacturer be implemented?

effervescent packaging

First, the operating procedures for the establishment of inspection results exceeding the limits of the investigation within the company. Laboratory investigation was carried out according to the regulations to confirm whether it was laboratory bias. If it is not the laboratory deviation, the R & D, technology and production personnel should be organized to investigate the production process. It can also be interpreted as two categories: laboratory bias and non laboratory bias.

133*29mm vitamin tablet tube

The laboratory deviation shall investigate any deviation of the test results caused by the factors related to the inspection process,A laboratory survey should be carried out by the professional personnel. The non laboratory deviation refers to the deviation of the test results caused by any other factors except the deviation of the laboratory. The above deviation analysis also standardizes the concrete implementation of the inspection results exceeding the standard for effervescent tablet tube factory. 

Vitamin C effervescent tube highlights differentiation

Vitamin C effervescent tablets are a common vitamin supplement that is very popular among young people. There are many manufacturers of vitamin C effervescent tablets on the market, and the phenomenon of product homogeneity is serious. In this context, the effervescent tube has become the key for pharmaceutical companies to break through the bottleneck of product development.

effervescent tablet tubes

Product competition is not only the competition of the product itself, but also the competition of the entire company and the competition of brands. When vitamin C effervescent tablets have similar taste and safety, the difference in packaging becomes a direct manifestation of product differentiation. Even two products with the same common name will have different market performance due to differences in packaging.

The effervescent tube is a special pharmaceutical packaging for vitamin C effervescent tablets. The effervescent tablet contains a disintegrant and is easily deteriorated by moisture. In order to ensure the dryness of the tablet, a desiccant made of silica gel and molecular sieve is placed inside the effervescent tube . Different from ordinary medicine bottles, the desiccant is stored on the top of the lid to prevent children from accidentally ingesting. The spiral spring on the lid can protect the tablet from damage due to various external forces.

In order to highlight the differentiation of brands and distinguish competing products, some pharmaceutical companies will use the color, logo, slogan, etc. of the effervescent tube to reflect it. For example, use different caps for different flavors of effervescent tablets, and add eye-catching slogans on the external label. In short, differentiation is a weapon for companies to break homogeneity. Only when there are differences can there be a market, and only then can they gain a place in the competition among the strong players.